Acquired Platelet Dysfunction with Eosinophilia (APDE) Syndrome: A Case Report
| Autor: | Rumma V. Manchanda, Diksha Dev Yadav, Priyanka S. Nayar |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Ecchymosis Case Report 030204 cardiovascular system & hematology Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Bleeding time hemic and lymphatic diseases Internal medicine medicine Eosinophilia Platelet Mean platelet volume Ristocetin education education.field_of_study medicine.diagnostic_test business.industry Hematology Purpura chemistry 030220 oncology & carcinogenesis Immunology Coagulation screen medicine.symptom business |
| Zdroj: | Indian Journal of Hematology and Blood Transfusion. 32:235-238 |
| ISSN: | 0974-0449 0971-4502 |
| Popis: | Acquired platelet dysfunction with eosinophilia (APDE) is a syndrome which has transient state of platelet dysfunction in the presence of marked eosinophilia. This bleeding disorder, otherwise known as “non-thrombocytopenic purpura with eosinophilia”, occurs commonly in children from South-East Asia. We report an 11 years old male child, who presented with ecchymotic patches over lower limbs, of recent onset. His hemogram revealed increased eosinophils with a normal platelet count. Coagulation screen revealed normal parameters except increase in bleeding time. Platelet aggregation studies showed normal platelet aggregation with ristocetin, reduced aggregation with ADP and no aggregation was seen with collagen. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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