Response to letter regarding article, 'Clinical impact of persistent left bundle-branch block after transcatheter aortic valve implantation with CoreValve revalving system'
| Autor: | Corrado Tamburino, Stefania Lanotte, Francesco Maisano, Federica Ettori, Mauro Agnifili, Jacopo Oreglia, Angelo Ramondo, Gian Paolo Ussia, Arnaldo Poli, Rosario Fiorilli, Luca Testa, Antonio Colombo, Azeem Latib, Roberto Latini, Antonio Marzocchi, Nedy Brambilla, Stefano De Servi, Federico De Marco, Marco De Carlo, Silvio Klugmann, Silvia Cirri, Anna Sonia Petronio, Giuseppe Tarantini, Samuele Pizzocri, Francesco Bedogni, Claudia Fiorina |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Cardiac Catheterization Transcatheter aortic medicine.medical_treatment Population Bundle-Branch Block Pacemaker implantation Valve replacement Physiology (medical) Internal medicine medicine Humans education Heart Valve Prosthesis Implantation education.field_of_study Left bundle branch block business.industry Aortic Valve Stenosis medicine.disease Surgery Cardiology Female Electrical conduction system of the heart Cardiology and Cardiovascular Medicine business Edwards sapien |
| Popis: | We appreciate the interest of Prinzen et al about our article,1 but some of their comments need to be addressed. Prinzen et al analyzed a mixed population of patients treated with CoreValve or Edwards Sapien prostheses.2 Of note, their different influence on the cardiac conduction system is well known,3 with the CoreValve being more prone to determine conduction disturbances as a consequence of the larger frame. Accordingly, we decided to specifically focus on the CoreValve, pooling >800 patients, which is more than double the population considered by Prinzen et al. It is clear that the internal and external validity (ie, the extent of systematic biases and the generalizability of the results) are highly affected by the sample size. Prinzen et al excluded patients who underwent pacemaker implantation within 30 days after transcatheter aortic valve replacement, which, in our opinion, makes little … |
| Databáze: | OpenAIRE |
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