Elevated C-reactive protein is significantly associated with left ventricular dysfunction in patients with aortic regurgitation and concomitant collagen disease

Autor: Kenshi Yamanaga, Hiroki Usuku, Hirotaka Matsui, Miwa Ito, Eiichiro Yamamoto, Taishi Nakamura, Koichiro Fujisue, Takashi Komorita, Kenichi Tsujita, Kenichi Matsushita, Momoko Noguchi, Seiji Takashio, Koichi Kaikita, Yuichiro Arima, Hisanori Kanazawa, Hirofumi Soejima, Daisuke Sueta, Masafumi Takae, Satoshi Araki, Hiroaki Kawano, Fumi Oike, Satoru Suzuki, Toshihiro Fukui
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Cardiology. 328:152-157
ISSN: 0167-5273
Popis: BACKGROUND Collagen disease is an important cause of aortic regurgitation (AR). Although aortic valve surgery is recommended for patients with AR and depressed left ventricular (LV) function, there have been few reports about risk factors for LV dysfunction in patients with AR concomitant with collagen disease. METHODS AND RESULTS We conducted this study at Kumamoto University Hospital in Japan. A total of 41 patients who had moderate to severe AR and concomitant collagen disease between January 2014 and December 2019 were enrolled. With regard to baseline characteristics, there were no significant differences in the type of collagen disease or El Khoury class between patients with preserved LV function and those with reduced LV function. B-type natriuretic peptide (375.2 [257.9-3852.6]pg/ml vs. 64.0 [33.3-133.6]pg/ml, p
Databáze: OpenAIRE