Treatment of Stage IV Malignant Rhabdoid Tumor of the Kidney (MRTK) With ICE and VDCy
| Autor: | Toshinori Hirama, Takanori Oda, Nobuo Mizue, Masaki Yamamoto, Jeffrey S. Dome, Yuki Kuroiwa, Shigeaki Yokoyama, Nobuhiro Suzuki, Tsukasa Hori, Akihiro Nui, Takashi Matsuno, Hiroyuki Tsutsumi, Naoki Hatakeyama, Tooru Kudoh, Masato Hareyama |
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| Rok vydání: | 2006 |
| Předmět: |
Oncology
medicine.medical_specialty Pathology Vincristine Cyclophosphamide medicine.medical_treatment chemistry.chemical_compound Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Doxorubicin Ifosfamide Rhabdoid Tumor Etoposide business.industry Remission Induction Infant Hematology Kidney Neoplasms Carboplatin Radiation therapy Regimen chemistry Pediatrics Perinatology and Child Health Female Cisplatin business medicine.drug |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 28:286-289 |
| ISSN: | 1077-4114 |
| DOI: | 10.1097/01.mph.0000212901.84146.5a |
| Popis: | The prognosis of stage IV malignant rhabdoid tumor of the kidney (MRTK) has been extremely poor. However, a combination of ICE (ifosfamide, carboplatin, and etoposide) and VDCy (vincristine, doxorubicin, and cyclophosphamide) was recently reported to be effective for metastatic MRTK. We describe a 21-month-old girl with stage IV MRTK who was successfully treated with ICE, VDCy, and radiotherapy. She remained well, without recurrence, 24 months after diagnosis. Alternating therapy with ICE and VDCy might become a standard regimen for stage IV MRTK, although further study is required to confirm its effectiveness. |
| Databáze: | OpenAIRE |
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