68Ga-DOTATOC-PET/CT–guided resection of a primary intraosseous meningioma: technical note
| Autor: | José de Jesús Martínez-Manrique, Nora Kerik-Rotenberg, Rodrigo Uribe-Pacheco, Gerardo Y. Guinto-Nishimura, Marcos V Sangrador-Deitos, Juan Luis Gómez-Amador |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Octreotide 030218 nuclear medicine & medical imaging Meningioma 03 medical and health sciences 0302 clinical medicine Positron Emission Tomography Computed Tomography Meningeal Neoplasms Organometallic Compounds medicine Humans Radiation treatment planning PET-CT medicine.diagnostic_test business.industry Technical note General Medicine Pathology Report medicine.disease Image-guided surgery Positron emission tomography Positron-Emission Tomography Surgery Neurology (clinical) Radiology Neoplasm Recurrence Local Tomography X-Ray Computed business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Neurosurgical Focus. 50:E6 |
| ISSN: | 1092-0684 |
| Popis: | Primary intraosseous meningiomas (PIMs) are rare tumors that present with a variable radiological appearance and a clinical behavior that is considerably different from that of intracranial meningiomas. Treatment of PIMs consists of complete resection, which may be difficult to achieve due to the lack of clear tumor margins on conventional imaging studies. PET/CT using 68Ga-DOTA–conjugated peptides has been used for the diagnosis and treatment planning of different types of meningiomas due to these tracers’ affinity to somatostatin receptors, which are found in most meningiomas. However, this imaging modality’s use as an intraoperative adjunct has not been reported for PIMs. In this technical note, the authors describe a [68Ga-DOTA0-Tyr3]octreotide (68Ga-DOTATOC)-PET/CT–guided resection of a PIM. In this case, the area of increased uptake in the 68Ga-DOTATOC-PET/CT study extended well beyond the tumor margins identified on MRI. The patient’s pathology report confirmed the presence of tumor cells within peripheral bone, which macroscopically appeared normal. The authors propose 68Ga-DOTATOC-PET/CT as a valuable adjunct in the surgical management of PIMs and offer a reasonable justification for its use based on current evidence. Its use for intraoperative image guidance may aid neurosurgeons in achieving a complete resection, thus minimizing the risk of recurrence of this complex pathological entity. |
| Databáze: | OpenAIRE |
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