Bioelectronics at the Single Molecule Level
| Autor: | Kristin N. Gabriel, Narendra Kumar, Tivoli J. Olsen, Deng Pan, Gregory A. Weiss, Denys Marushchak, O. Tolga Gul, Kaitlin M. Pugliese, Calvin J Lau, Philip G. Collins, Yongki Choi, Arith J. Rajapakse |
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| Předmět: |
Bioelectronics
Materials science biology Aptamer A protein Nanotechnology 02 engineering and technology Biochemical Activity 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences biology.protein High bandwidth Molecule DNA polymerase I 0210 nano-technology |
| Zdroj: | Web of Science |
| Popis: | Bioelectronic devices built with single molecules of a protein, enzyme, or aptamer represent a new class of hybrid electronics. When biofunctionalization of nanoscale conductors is reduced to one molecule, that molecule's dynamic activity can be transduced into a large amplitude, high bandwidth electronic output. Using DNA polymerase I as an example, we show that single-molecule bioelectronics reveal biochemical activity with bond-by-bond resolution. |
| Databáze: | OpenAIRE |
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