T2* Mapping of the Hip in Asymptomatic Volunteers with Normal Cartilage Morphology: An Analysis of Regional and Age-Dependent Distribution
| Autor: | Gerald Antoch, Rüdiger Krauspe, Harish S. Hosalkar, Christoph Zilkens, Christoph Schleich, Alexander Buchwald, Bernd Bittersohl, Tobias Hesper |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Cartilage Articular Male Volunteers medicine.medical_specialty T2 mapping Population Biomedical Engineering Physical Therapy Sports Therapy and Rehabilitation Asymptomatic 030218 nuclear medicine & medical imaging 03 medical and health sciences Femoral head Young Adult 0302 clinical medicine Age Distribution Clinical Cartilage Papers medicine Immunology and Allergy Humans education education.field_of_study medicine.diagnostic_test business.industry Cartilage Magnetic resonance imaging Acetabulum Femur Head Middle Aged Magnetic Resonance Imaging Surgery medicine.anatomical_structure 030220 oncology & carcinogenesis Cohort Female Hip Joint medicine.symptom business Nuclear medicine |
| Zdroj: | Cartilage. 9(1) |
| ISSN: | 1947-6043 |
| Popis: | Objective To assess age-dependent and regional differences in T2* relaxation measurements in hip joint cartilage of asymptomatic volunteers at 3 T. Design Three age cohorts (cohort 1: age 20-30 years, 15 individuals; cohort 2: age 30-40 years, 17 individuals; cohort 3: age 40-50 years, 15 individuals) were enrolled. T2* values were obtained in the central and peripheral cartilage of the acetabulum and the femoral head in 7 regions (anterior to superior and posterior). Results T2* did not differ among age cohorts in acetabular cartilage (cohort 1: 24.65 ± 6.56 ms, cohort 2: 24.70 ± 4.83 ms, cohort 3: 25.81 ± 5.10 ms, P = 0.10) and femoral head cartilage (cohort 1: 27.08 ± 8.24 ms, cohort 2: 25.90 ± 7.82 ms, cohort 3: 26.50 ± 5.61 ms, P = 0.34). Analysis of the regional T2* distribution pattern indicates increased T2* values in the anterior, anterior-superior, superior-anterior, and the posterior-superior aspects of acetabular and femoral head cartilage. For acetabular cartilage, higher values were observed in the central region (25.90 ± 4.80 ms vs. 24.21 ± 4.05 ms, P < 0.0001) whereas femoral head cartilage did not reveal such differences (26.62 ± 5.74 ms vs. 26.37 ± 5.89 ms, P = 0.44). Conclusions The T2* analysis of presumably healthy hip joint cartilage does not seem to be stratified according to age in this population. Regional T2* variation throughout hip joint cartilage is apparent in this modality. |
| Databáze: | OpenAIRE |
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