Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni

Autor:	Clarice Neuenschwander Lins de Morais, Marcílio L Aroucha, Lilian Beck, Wlademir G. Melo, Daniele Silva de Moraes Van-Lume, Silvia Maria Lucena Montenegro, Constança Simões Barbosa, Frederico G. C. Abath, Joelma Rodrigues de Souza, Otávio Sarmento Pieri, Ana Lúcia Coutinho Domingues, Tereza Cristina Favre, Edeneide Maria Xavier
Jazyk:	angličtina
Rok vydání:	2004
Předmět:	Microbiology (medical) keyhole limpet haemocyanin lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Antibodies Helminth lcsh:QR1-502 Enzyme-Linked Immunosorbent Assay Schistosomiasis chemical and pharmacologic phenomena Sensitivity and Specificity complex mixtures lcsh:Microbiology Antigen medicine soluble egg antigens Animals Humans In patient Acute schistosomiasis biology hemic and immune systems Helminth Proteins Schistosoma mansoni biology.organism_classification medicine.disease Schistosomiasis mansoni Antibody response Immunoglobulin M Antigens Helminth Immunoglobulin G Acute Disease Chronic Disease Hemocyanins Immunology biology.protein Antibody Biomarkers Keyhole limpet hemocyanin enzime-linked immunosorbent assay
Zdroj:	Memórias do Instituto Oswaldo Cruz., Vol 99, Pp 97-98 (2004) Memórias do Instituto Oswaldo Cruz, Volume: 99 Supplement 1, Pages: 97-98, Published: AUG 2004
ISSN:	1678-8060 0074-0276
Popis:	Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.
Databáze:	OpenAIRE
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