Isolation and Characterization of Ovine Testicular and Ovarian Inhibin
| Autor: | S. B. Moodbidri, Lata Joshi, Atmaram H. Bandivdekar, S. Vijayalakshmi, Anil R. Sheth |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Serum fsh endocrine system diseases Adult male Ovary Biology Kidney Ovarian weight Gonadotropin-Releasing Hormone Endocrinology Inhibin activity Internal medicine Biological property Testis medicine Animals Inhibins Sheep Proteins Luteinizing Hormone Hormones Testicular Hormones Ovarian Inhibin medicine.anatomical_structure Liver Female Follicle Stimulating Hormone hormones hormone substitutes and hormone antagonists |
| Zdroj: | Archives of Andrology. 5:179-188 |
| ISSN: | 0148-5016 |
| DOI: | 10.3109/01485018008986313 |
| Popis: | Low-molecular-weight (< 1500 daltons) peptides with inhibin activity have been isolated from sheep testes and ovaries by simple gel filtration. These peptides were capable of inhibiting the ovarian weight increase in hCG-primed immature female mice and also of suppressing the post-castration rise of serum FSH levels in adult male rats, suggesting similarities in their biological properties. Both testicular and ovarian inhibin were typsin sensitive and heat stable at 100 degrees C for 30 min and were shown to act by interfering with the production of a hypothetical FSH-RH. |
| Databáze: | OpenAIRE |
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