Oxygen consumption and sodium pump thermogenesis in a developing mammal
| Autor: | P. L. Else |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
Aging Physiology Sodium chemistry.chemical_element Diaphragm pump Oxygen Animal science Oxygen Consumption Physiology (medical) Respiration Animals skin and connective tissue diseases Ouabain Chemistry Body Weight Metabolism Organ Size Rats Liver metabolism Biochemistry Liver Sodium pump Female sense organs Sodium-Potassium-Exchanging ATPase Energy Metabolism Thermogenesis Body Temperature Regulation |
| Zdroj: | The American journal of physiology. 261(6 Pt 2) |
| ISSN: | 0002-9513 |
| Popis: | During development the liver undergoes large changes in its oxygen consumption. The energy requirements of the sodium pump (i.e., ouabain-sensitive respiration) would appear to account for a major part of these changes. In very young rats (birth to 9 days), the sodium pump accounted for approximately 50% of a high weight-specific liver metabolism (LMR). In rats greater than or equal to 20 days of age, the sodium pump accounted for a smaller percentage (33%) of a much lower LMR. These changes scaled with body mass. LMR scaled with an allometric slope of -0.258, ouabain-sensitive respiration with a slope of -0.355, and ouabain-insensitive respiration with a slope of -0.194. It is proposed that changes in LMR of rats during development are due primarily to the changing energy requirements of the sodium pump. |
| Databáze: | OpenAIRE |
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