Infiltration of the basal ganglia by brain tumors is associated with the development of co-dominant language function on fMRI
| Autor: | Robert J. Young, Katharina Shaw, Zhigang Zhang, Kyung K. Peck, Andrei I. Holodny, Kaitlin M. Woo, Nicole Petrovich Brennan |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Linguistics and Language Cognitive Neuroscience Brain tumor Experimental and Cognitive Psychology Language and Linguistics Basal Ganglia Functional Laterality Article 030218 nuclear medicine & medical imaging 03 medical and health sciences Speech and Hearing 0302 clinical medicine Text mining Aphasia Basal ganglia medicine Humans Dominance (genetics) Aged Language Brain Mapping medicine.diagnostic_test business.industry Brain Neoplasms Middle Aged medicine.disease Magnetic Resonance Imaging Boston Naming Test Speech Perception Female medicine.symptom business Functional magnetic resonance imaging Psychology Neuroscience Infiltration (medical) 030217 neurology & neurosurgery |
| Zdroj: | Brain and language. |
| ISSN: | 1090-2155 |
| Popis: | Studies have shown that some patients with left-hemispheric brain tumors have an increased propensity for developing right-sided language support. However, the precise trigger for establishing co-dominant language function in brain tumor patients remains unknown. We analyzed the MR scans of patients with left-hemispheric tumors and either co-dominant (n=35) or left-hemisphere dominant (n=35) language function on fMRI to investigate anatomical factors influencing hemispheric language dominance. Of eleven neuroanatomical areas evaluated for tumor involvement, the basal ganglia was significantly correlated with co-dominant language function (p |
| Databáze: | OpenAIRE |
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