Relationship of immediate and delayed hypersensitivity to nasopharyngeal and intestinal growth of Candida albicans in allergic subjects
| Autor: | Kirsti Kalimo, Markku Viander, A. Koivikko, E. Nieminen |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Hypersensitivity Immediate Male Allergy Immunology Anal Canal Immunoglobulin E Nasopharynx Candida albicans otorhinolaryngologic diseases medicine Humans Immunology and Allergy Hypersensitivity Delayed Asthma Immunity Cellular biology business.industry Middle Aged respiratory system Anal canal biology.organism_classification medicine.disease Anus Corpus albicans medicine.anatomical_structure Delayed hypersensitivity biology.protein Female business |
| Zdroj: | Allergy. 43:201-205 |
| ISSN: | 0105-4538 |
| Popis: | The growth of C. albicans yeast in the nasopharynx and in the anus as well as allergy symptoms were followed up for 8 months in 67 patients with bronchial asthma, allergic rhinitis and/or atopic eczema. 38 of the patients were skin prick test positive and 29 negative to C. albicans allergen extract. 32 of the patients had positive and 19 negative delayed skin reactions. The nasal, bronchial and skin symptoms of the yeast-sensitive allergic patients were not associated with the nasopharyngeal nor anal occurrence of C. albicans or other yeasts. The use of nasal or inhaled steroids had no effect on the occurrence of Candida in the nasopharynx. It was observed that immediate skin sensitivity had a positive correlation and the delayed sensitivity a negative correlation with the occurrence of C. albicans growth in nasopharynx and anus. These findings are in agreement with the concept that impaired cell-mediated immunity to C. albicans may lead to increased IgE response. This may explain the increased liability towards C. albicans nasopharyngeal and gastrointestinal "saprophytic" growth. |
| Databáze: | OpenAIRE |
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