STOP-Bang questionnaire should be used in all adults with Down Syndrome to screen for moderate to severe obstructive sleep apnea

Autor: de Carvalho Sr., Anderson Albuquerque, Amorim II, Fabio Ferreira, Santana III, Levy Aniceto, de Almeida IV, Karlo Josefo Quadros, Santana V, Alfredo Nicodemos da Cruz, Neves VI, Francisco de Assis Rocha
Rok vydání: 2020
Předmět:
Male
Questionnaires
Physiology
Cross-sectional study
Peptide Hormones
Polysomnography
Biochemistry
Pittsburgh Sleep Quality Index
Chromosomal Disorders
Mathematical and Statistical Techniques
0302 clinical medicine
Surveys and Questionnaires
Bayesian multivariate linear regression
Medicine and Health Sciences
Clinical Neurophysiology
Sleep Apnea
Obstructive
education.field_of_study
Multidisciplinary
medicine.diagnostic_test
Epworth Sleepiness Scale
Statistics
Sleep apnea
Hematology
Body Fluids
Blood
Hematocrit
Neurology
Research Design
Physical Sciences
Regression Analysis
Medicine
Female
Anatomy
Research Article
Moderate to severe
Adult
Down syndrome
medicine.medical_specialty
Science
Population
Linear Regression Analysis
Research and Analysis Methods
Young Adult
03 medical and health sciences
Internal medicine
medicine
Humans
Statistical Methods
Thyroid-Stimulating Hormone
education
Clinical Genetics
Survey Research
business.industry
Biology and Life Sciences
medicine.disease
Hormones
respiratory tract diseases
Blood Counts
Obstructive sleep apnea
Cross-Sectional Studies
030228 respiratory system
Down Syndrome
Clinical Medicine
Physiological Processes
Sleep
Sleep Disorders
business
Mathematics
030217 neurology & neurosurgery
Zdroj: PLoS ONE, Vol 15, Iss 5, p e0232596 (2020)
PLoS ONE
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0232596
Popis: Study ObjectivesTo determine the prevalence of obstructive sleep apnea (OSA) in adults with Down syndrome (DS), to investigate factors related to OSA severity and to identify which sleep questionnaire is the most appropriate for the screening of OSA in this population.MethodsCross-sectional study that consecutively included 60 adults with DS. All patients underwent type III polysomnography and clinical and laboratory data were collected; sleep assessment questionnaires were applied. Multiple linear regression models evaluated the associations between OSA severity (measured by the respiratory event index - REI) and clinical and laboratory data and sleep questionnaires (Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, BERLIN and STOP-Bang questionnaires).ResultsResults show that 60 (100%) adults with DS had OSA, with moderate-severe OSA identified in 49 (81.6%). At the multivariate linear regression, REI significantly correlated with hematocrit levels, BMI and STOP-Bang questionnaire (SBQ) results (P ConclusionsAdults with DS have a very high prevalence of OSA. Hematocrit levels, BMI and SBQ showed a strong correlation with OSA severity. The SBQ performed well in identifying moderate to severe OSA in this population. Considered together, these results point to the need to perform OSA screening in all adults with DS, and STOP-Bang may play a role in this screening.
Databáze: OpenAIRE
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