Calibration of a total body potassium monitor with an anthropomorphic phantom

Autor: Barry J. Allen, R D Hansen
Rok vydání: 1996
Předmět:
Zdroj: Physics in Medicine and Biology. 41:2447-2462
ISSN: 1361-6560
0031-9155
DOI: 10.1088/0031-9155/41/11/015
Popis: An anthropomorphic phantom was used to calibrate a supine geometry sodium iodide total body potassium monitor. Correction factors accommodating variability in subject size were empirically determined. Measurements on 12 males of weight 45-96 kg, height 161-184 cm and 18 females of weight 48-89 kg, height 153-175 cm, showed that the 40K calibration factor (F, counts s-1 (g of potassium)-1) was significantly correlated (r = 0.88, p0.0001) to subject (weight/height)0.5, indicating comparable accuracy to 42K-based calibration procedures. Fat-free mass determined from the potassium measurements of 16 subjects correlated significantly with fat-free mass estimated from skinfold thickness (r = 0.98, p0.0001), dual-energy x-ray absorptiometry (r = 0.99, p0.0001) and bioimpedance analysis (r = 0.98, p0.0001). These data, together with the precision (coefficient of variation, CV = 1.5%) and accuracy (CV = 4.5%) of the system, indicate that this calibration procedure represents a relatively low-cost, non-invasive alternative to 42K-based methods of calibrating total body potassium monitors.
Databáze: OpenAIRE