Tailoring Silica-Based Nanoscintillators for Peroxynitrite-Potentiated Nitrosative Stress in Postoperative Radiotherapy of Colon Cancer

Autor:	Shikai Liu, Wenting Li, Yangyang Zhang, Jialing Zhou, Yaqian Du, Shuming Dong, Boshi Tian, Linyang Fang, He Ding, Shili Gai, Piaoping Yang
Rok vydání:	2022
Předmět:	Nitrosative Stress Peroxynitrous Acid Mechanical Engineering Colonic Neoplasms Humans General Materials Science Bioengineering General Chemistry Nitric Oxide Silicon Dioxide Condensed Matter Physics Reactive Nitrogen Species
Zdroj:	Nano Letters. 22:6409-6417
ISSN:	1530-6992 1530-6984
Popis:	The development of a manageable reactive nitrogen species-potentiated nitrosative stress induction system for cancer therapy has remained elusive. Herein, tailored silica-based nanoscintillators were reported for low-dosage X-ray boosting for the in situ formation of highly cytotoxic peroxynitrite (ONOO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075c3ba14187b152391f4e845b161d3a https://doi.org/10.1021/acs.nanolett.2c02472 Zobrazit plný text záznamu