Study of the Efficacy of PET/CT in Lung Aspiration Biopsy and Factors Associated with False-Negative Results
| Autor: | Ahrong Kim, Geewon Lee, Il Wan Son, Ji Won Lee, Yeon Joo Jeong, Hie Bum Suh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty PET-CT medicine.diagnostic_test business.industry lcsh:R895-920 multidetector computed tomography lung neoplasms 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine pet-ct Lung aspiration 030220 oncology & carcinogenesis Biopsy Multidetector computed tomography medicine Radiology Nuclear Medicine and imaging Radiology business |
| Zdroj: | 대한영상의학회지, Vol 79, Iss 3, Pp 129-138 (2018) |
| ISSN: | 2288-2928 1738-2637 |
| Popis: | Purpose: We compared the outcomes of percutaneous transthoracic needle aspiration biopsy (PCNA) of lung masses in cases with and without prior positron emission tomography/computed tomography (PET/CT) information, and investigated the factors associated with false-negative pathological results. Materials and Methods: From a total of 291 patients, 161 underwent PCNA without prior PET/CT imaging, while 130 underwent PET/CT before PCNA. Clinical characteristics, procedural variables, pathological results, and diagnostic success rates were compared between the 2 groups. Among patients with initial negative (non-specific benign) PCNA results, the radiological findings of these groups were compared to evaluate the predictors of false-negative lesions. Results: No significant difference was found in the clinical characteristics, procedural characteristics, and pathological results of the 2 groups, nor was the diagnostic rate significantly different between them (p = 0.818). Among patients with initial negative PCNA results, radiological characteristics were similar in both the groups. In multivariate analysis, the presence of necrosis (p = 0.005) and ground-glass opacity (GGO) (p = 0.011) were the significant characteristics that indicated an increased probability of initial false-negative results in PCNA. Conclusion: Routine PET/CT did not have any additional benefit in patients undergoing PCNA of lung masses. The presence of necrosis or GGO could indicate an increased probability of false-negative pathological results. |
| Databáze: | OpenAIRE |
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