Gabor Domain Optical Coherence Microscopy

Autor: Jannick P. Rolland, Kye-Sung Lee, Kevin P. Thompson, Panomsak Meemon, Ilhan Kaya, Nicolene Papp, Supraja Murali
Rok vydání: 2009
Předmět:
Zdroj: Optical Coherence Tomography and Coherence Techniques IV.
DOI: 10.1364/ecbo.2009.7372_1k
Popis: In this paper, we present a developing technology targeted at clinical imaging, Gabor Domain Optical Coherence Microscopy (GD-OCM), which combines the high resolution imaging of optical coherence microscopy (OCM), high imaging speed of Fourier domain optical coherence tomography (FD-OCT), and invariant lateral resolution of our custom designed dynamic focusing objective. A high lateral resolution optical design of a dynamic-focusing optical probe with no moving parts, which provides an invariant resolution of currently < 3 µm across a 2mm full-field of view and 2mm imaging depth, is presented. Furthermore, an acquisition scheme (using the probe) that is capable of performing automatic real time data fusion to render an in-focus high resolution image throughout the depth of sample in real time was implemented. 3D imaging of an African frog tadpole is demonstrated at cellular level resolution.
Databáze: OpenAIRE