Gabor Domain Optical Coherence Microscopy
Autor: | Jannick P. Rolland, Kye-Sung Lee, Kevin P. Thompson, Panomsak Meemon, Ilhan Kaya, Nicolene Papp, Supraja Murali |
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Rok vydání: | 2009 |
Předmět: |
Physics
Image fusion Microscope medicine.diagnostic_test business.industry Resolution (electron density) Spectral density Stereoscopy Sensor fusion Sample (graphics) law.invention Optics Optical coherence tomography Optical microscope law Microscopy medicine Astronomical interferometer Computer vision Artificial intelligence business |
Zdroj: | Optical Coherence Tomography and Coherence Techniques IV. |
DOI: | 10.1364/ecbo.2009.7372_1k |
Popis: | In this paper, we present a developing technology targeted at clinical imaging, Gabor Domain Optical Coherence Microscopy (GD-OCM), which combines the high resolution imaging of optical coherence microscopy (OCM), high imaging speed of Fourier domain optical coherence tomography (FD-OCT), and invariant lateral resolution of our custom designed dynamic focusing objective. A high lateral resolution optical design of a dynamic-focusing optical probe with no moving parts, which provides an invariant resolution of currently < 3 µm across a 2mm full-field of view and 2mm imaging depth, is presented. Furthermore, an acquisition scheme (using the probe) that is capable of performing automatic real time data fusion to render an in-focus high resolution image throughout the depth of sample in real time was implemented. 3D imaging of an African frog tadpole is demonstrated at cellular level resolution. |
Databáze: | OpenAIRE |
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