Radiodermatitis in Patients With Cancer: Systematic Review and Meta-Analysis
| Autor: | Elizabeth Croson, Mark Vrabel, Kerri A. Moriarty, Rebecca L. Morgan, Lindsey N. Horrell, Pamela K. Ginex, Chelsea Backler, Christine Maloney |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
030504 nursing Symptom management business.industry Cancer Guideline medicine.disease Bandages Dermatology 03 medical and health sciences Moist desquamation Neoplasms Meta-analysis medicine Humans Itching Radiodermatitis In patient medicine.symptom 0305 other medical science business |
| Zdroj: | Oncology Nursing Forum. 47:E225-E236 |
| ISSN: | 1538-0688 0190-535X |
| DOI: | 10.1188/20.onf.e225-e236 |
| Popis: | Problem identification A systematic review and meta-analysis was conducted to inform the development of guidelines on the management of radiodermatitis among patients with cancer. Literature search The authors updated a systematic review to include available literature published through September 30, 2019. Data evaluation Two investigators assessed risk of bias using the Cochrane Collaboration risk-of-bias tool and certainty of the evidence using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. Synthesis The use of deodorant/antiperspirant had no effect on development of radiodermatitis. Aloe vera and emu oil were equivalent or less effective than standard care. Oral curcumin had a minimal beneficial effect. Nonsteroidal topical interventions had a minimal beneficial effect on the development of moist desquamation and relief of itching while causing a small increase for grade 2 radiodermatitis. Topical calendula increased risk for the development of radiodermatitis. Topical steroids and dressings each showed benefits to minimize the development of radiodermatitis and moist desquamation while lowering rates of patient-reported symptoms, such as pain and pruritus. Implications for research Symptom management strategies for radiodermatitis among patients with cancer that are likely to be effective include topical nonsteroidals, topical steroids, and dressings. Supplemental material can be found at https //bit.ly/2FWj3Kp. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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