Effects of water-aging for 6 months on the durability of a novel antimicrobial and protein-repellent dental bonding agent
| Autor: | Hockin H.K. Xu, Ning Zhang, David J. Xu, Ke Zhang, Michael D. Weir, Mark A. Reynolds, Yuxing Bai |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Surface Properties
Phosphorylcholine Dental Bonding Agent Dentistry 02 engineering and technology Dental bonding Dental plaque 03 medical and health sciences 0302 clinical medicine Anti-Infective Agents stomatognathic system Materials Testing Dentin medicine General Dentistry Antibacterial agent business.industry Chemistry Bond strength Biofilm Dental Bonding Water 030206 dentistry 021001 nanoscience & nanotechnology medicine.disease Resin Cements lcsh:RK1-715 stomatognathic diseases medicine.anatomical_structure Biofilms Dentin-Bonding Agents lcsh:Dentistry Methacrylates Adhesive 0210 nano-technology business Shear Strength |
| Zdroj: | International Journal of Oral Science, Vol 10, Iss 2, Pp 1-8 (2018) |
| ISSN: | 2049-3169 |
| Popis: | Biofilms at the tooth-restoration bonded interface can produce acids and cause recurrent caries. Recurrent caries is a primary reason for restoration failures. The objectives of this study were to synthesize a novel bioactive dental bonding agent containing dimethylaminohexadecyl methacrylate (DMAHDM) and 2-methacryloyloxyethyl phosphorylcholine (MPC) to inhibit biofilm formation at the tooth-restoration margin and to investigate the effects of water-aging for 6 months on the dentin bond strength and protein-repellent and antibacterial durability. A protein-repellent agent (MPC) and antibacterial agent (DMAHDM) were added to a Scotchbond multi-purpose (SBMP) primer and adhesive. Specimens were stored in water at 37 °C for 1, 30, 90, or 180 days (d). At the end of each time period, the dentin bond strength and protein-repellent and antibacterial properties were evaluated. Protein attachment onto resin specimens was measured by the micro-bicinchoninic acid approach. A dental plaque microcosm biofilm model was used to test the biofilm response. The SBMP + MPC + DMAHDM group showed no decline in dentin bond strength after water-aging for 6 months, which was significantly higher than that of the control (P 0.1). In conclusion, a bonding agent with MPC and DMAHDM achieved a durable dentin bond strength and long-term resistance to proteins and oral bacteria. The novel dental bonding agent is promising for applications in preventive and restorative dentistry to reduce biofilm formation at the tooth-restoration margin. A strong, long-lasting bonding agent developed by researchers in the US and China can protect tooth restorations from bacteria and proteins. Tooth restorations often fail due to recurrent decay which starts when bacteria invade the interface between the tooth and the restoration material, producing acids. To combat this problem, Ning Zhang at the University of Maryland, Baltimore, and Capital Medical University, Beijing, and co-workers infused the commercial Scotchbond Multi-Purpose primer and adhesive with two chemicals known to inhibit the formation of bacterial biofilms. The team stored bonded teeth in warm water for six months, after which they found no decline in the bond strength, or its resistance to oral proteins and bacteria. They hope that by incorporating the same protective chemicals into cements, composites and sealants, failure rates in tooth restorations could be reduced. |
| Databáze: | OpenAIRE |
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