Carbon dioxide insufflationvsconventional air insufflation for colonoscopy: a systematic review and meta-analysis of published randomized controlled trials

Autor: M. S. Sajid, W. F. A. Miles, Muhammad I. Bhatti, Mirza K. Baig, J. Caswell, P. Sains
Rok vydání: 2015
Předmět:
Zdroj: Colorectal Disease. 17:111-123
ISSN: 1462-8910
DOI: 10.1111/codi.12837
Popis: Aim Conventional air insufflation (AI) may cause prolonged abdominal bloating, excessive abdominal pain and discomfort during colonoscopy. Carbon dioxide may be an acceptable alternative to avoid these complications. The object of this study was to evaluate systematically the effectiveness of carbon dioxide insufflation (CI) for colonoscopy compared with AI. Method Randomized controlled trials (RCTs) comparing the effectiveness of CI with that of AI during colonoscopy were retrieved from medical electronic databases and combined analysis was performed using the RevMan statistical package. The combined outcome of dichotomous and continuous variables was expressed as an odds ratio (OR) and standardized mean difference (SMD). Results Twenty-one RCTs comprising 3607 patients were included in the study. There was statistically significant heterogeneity among included studies. CI showed a significant trend towards reduced procedural pain [SMD –1.34; 95% confidence interval (95% CI) −2.23 to −0.45; z = 2.96; P
Databáze: OpenAIRE