Polyamines: Emerging players in bacteria-host interactions
| Autor: | Maria Assunta Casalino, Gianni Prosseda, Maria Letizia Di Martino, Gioacchino Micheli, Bianca Colonna, Rosaria Campilongo |
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| Přispěvatelé: | Dipartimento di Biologia, Università degli Studi Roma Tre, Department of Biology and Biotechnology 'Charles Darwin', Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Istituto di Biologia e Patologia Molecolari CNR, This work was supported by grants from MIUR (PRIN, FIRB, Progetto Ateneo)., Di Martino, Maria Letizia, Campilongo, Rosaria, Casalino, Maria Assunta, Micheli, Gioacchino, Colonna, Bianca, Prosseda, Gianni |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Microbiology (medical)
Bacterial Physiological Phenomena Bacterial-host interactions Microbiology Bacterial evolution 03 medical and health sciences Polyamines Humans Pathogenicity MESH: Polyamines 030304 developmental biology 0303 health sciences MESH: Humans biology Bacteria 030306 microbiology Host (biology) MESH: Host-Pathogen Interactions Bacterial pathogenesis polyamines bacterial pathogens bacterial-host interactions pathogenicity bacterial evolution General Medicine biology.organism_classification Cell biology MESH: Bacteria Infectious Diseases [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology MESH: Bacterial Physiological Phenomena Host-Pathogen Interactions Bacterial pathogens Polyamines Bacterial pathogens Pathogenicity Bacterial–host interactions Bacterial evolution |
| Zdroj: | International journal of medical microbiology 303 (2013): 484–491. doi:10.1016/j.ijmm.2013.06.008 info:cnr-pdr/source/autori:Di Martino, Maria Letizia; Campilongo, Rosaria; Casalino, Mariassunta; Micheli, Gioacchino; Colonna, Bianca; Prosseda, Gianni/titolo:Polyamines: Emerging players in bacteria-host interactions/doi:10.1016%2Fj.ijmm.2013.06.008/rivista:International journal of medical microbiology (Print)/anno:2013/pagina_da:484/pagina_a:491/intervallo_pagine:484–491/volume:303 International Journal of Medical Microbiology International Journal of Medical Microbiology, Elsevier, 2013, 303 (8), pp.484-91. ⟨10.1016/j.ijmm.2013.06.008⟩ |
| ISSN: | 1438-4221 |
| DOI: | 10.1016/j.ijmm.2013.06.008 |
| Popis: | International audience; Polyamines are small polycationic molecules found in almost all cells and associated with a wide variety of physiological processes. In recent years it has become increasingly clear that, in addition to core physiological functions, polyamines play a crucial role in bacterial pathogenesis. Considerable evidence has built up that bacteria have evolved mechanisms to turn these molecules to their own advantage and a novel standpoint to look at host-bacterium interactions emerges from the interplay among polyamines, host cells and infecting bacteria. In this review, we highlight how human bacterial pathogens have developed their own resourceful strategies to exploit polyamines or manipulate polyamine-related processes to optimize their fitness within the host. Besides contributing to a better understanding of the complex relationship between a pathogen and its host, acquisitions in this field have a significant potential towards the development of novel antibacterial therapeutic approaches. |
| Databáze: | OpenAIRE |
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