Clinical outcomes of curative treatment for colorectal liver metastases combined with cytoreductive surgery and intraperitoneal chemotherapy for peritoneal metastases: a systematic review and meta-analysis of current evidence
| Autor: | Xinzhi Zhang, Jia-wei Cai, Zhi-hong Shen, Yu-ming Rong, Ying-xin Tan, Yifeng Zou, Jing-rong Weng, Xutao Lin, Xi Chen |
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| Rok vydání: | 2020 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Peritoneal metastasis Physiology Colorectal cancer colorectal cancer intraperitoneal chemotherapy 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Physiology (medical) Internal medicine Medical technology Humans cytoreductive surgery Medicine R855-855.5 Peritoneal Neoplasms business.industry Optimal treatment Liver Neoplasms Intraperitoneal chemotherapy Cytoreduction Surgical Procedures Hyperthermia Induced Prognosis medicine.disease Combined Modality Therapy Peritoneal carcinomatosis Survival Rate liver metastasis Curative treatment peritoneal metastasis 030220 oncology & carcinogenesis Meta-analysis Neoplasm Recurrence Local Colorectal Neoplasms business Cytoreductive surgery |
| Zdroj: | International Journal of Hyperthermia, Vol 37, Iss 1, Pp 944-954 (2020) |
| ISSN: | 1464-5157 0265-6736 |
| DOI: | 10.1080/02656736.2020.1803424 |
| Popis: | Background The optimal treatment for colorectal cancer (CRC) with synchronous peritoneal carcinomatosis (PC) and liver metastases (LM) remains controversial. We aimed to investigate clinical outcomes in patients with CRC and concomitant PC and LM who had undergone curative surgery, including resections at both metastatic sites and synchronous intraabdominal chemotherapy. Methods We searched PubMed, EMBASE, and Web of Science databases for eligible studies. Studies focusing on the clinical effects of curative surgery and synchronous intraabdominal chemotherapy for patients with CRC and concomitant PC and LM were included. Meta-analysis results were recorded as hazard ratios (HRs), risk ratios (RRs) and mean differences. Results We included 9 of 998 identified studies in the meta-analysis, involving 746 patients (221 patients with PC + LM, 525 patients with PC). Overall survival (pooled HR 1.68, 95% confidence interval [CI] 1.33–2.13, p |
| Databáze: | OpenAIRE |
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