| Autor: |
Lu-Zhe Sun, Ismail Jatoi, Virginia Kaklamani, Andrew J. Brenner, Alia Nazarullah, Larry E. Broome, Guixi Zheng, Bingzhi Wang, Hakim Bouamar, Kyle Pressley, Xiao-Fei Ding, Guang Chen |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1078-0432.22479284 |
| Popis: |
mTOR inhibition decreases MMP9 expression. A, Everolimus treatment for 24 hours did not reduced MMP2 protein levels in SUM225 cells. B, C and D figures were the MMP-9 IHC quantification data measuring average optical density using ImageJ d 1.47 software. B, one-week Everolimus treatments at 2 mg/kg/day significantly decreased MMP9 protein levels in the mammary gland of MMTV/neu mice (n=3). C, one-week-Everolimus treatments at 2 mg/kg decreased MMP9 protein levels in the mammary gland of SUM225-MIND mouse mammary tissues detected by IHC (n=4). D, one-week-rapamycin treatments at 2 mg/day reduced MMP9 protein levels in mammary glands of DCIS patients detected by IHC. **p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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