Periodicity and patterns of Entamoeba histolytica and E. dispar infection in HIV+/AIDS patients in Mexico
| Autor: | Patricia Morán, Cecilia Ximénez, A. Gómez, Enrique González, Gabriela García, Emma I. Melendro, Fernando Ramos, Alicia Valadez, Angélica Limón, Liliana Rojas, Olivia Valenzuela, C. Riebeling |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Dispar Statistics as Topic HIV Infections Lobosea Polymerase Chain Reaction Host-Parasite Interactions Entamoeba Entamoeba histolytica fluids and secretions parasitic diseases Genetic variation HIV Seropositivity medicine Prevalence Animals Humans Amoebiasis Longitudinal Studies Mexico Aged biology Entamoebiasis AIDS-Related Opportunistic Infections Chitinases Amplicon Middle Aged biology.organism_classification medicine.disease Virology Infectious Diseases HIV-1 Parasitology Female |
| Zdroj: | Annals of tropical medicine and parasitology. 103(4) |
| ISSN: | 0003-4983 |
| Popis: | In a 12-month longitudinal study, a cohort of Mexican HIV+/AIDS patients was checked several times for Entamoeba infection, with the parasites identified, as E. histolytica or E. dispar, using PCR. The polymorphic region of the parasites' chitinase genes was investigated by PCR, with the variation in amplicon sizes being used as a measure of the genetic variation among the isolates. The patients found infected with Entamoeba at the start of the study displayed varied patterns of infection clearance and re-infection. The analysis of the polymorphisms in the chitinase gene revealed seven polymorphic patterns in the E. histolytica isolates investigated and three in the E. dispar isolates. Many of the patients were each re-infected with Entamoeba at least once during the 12 months of follow-up. As seen in a previous study in Mexico, none of the E. histolytica-infected patients developed any clinical symptoms of invasive amoebiasis during the follow-up period. The results highlight the complexity of the host-parasite relationship in human amoebiasis. |
| Databáze: | OpenAIRE |
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