Relation of C-Reactive Protein to the First Onset and the Recurrence Rate in Lone Atrial Fibrillation
| Autor: | Nikolaos Papanas, Dimitrios Floros, Efstratios Maltezos, Dimitrios Tziakas, Dimitrios Stakos, Dimitrios I. Hatseras, Athanasios Hotidis, Eleni Hatzinikolaou-Kotsakou, Georgios K. Chalikias |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Heart disease Systemic inflammation Predictive Value of Tests Recurrence Interquartile range Internal medicine Atrial Fibrillation medicine Humans Proportional Hazards Models Analysis of Variance biology business.industry Hazard ratio C-reactive protein Age Factors Atrial fibrillation Middle Aged medicine.disease Confidence interval C-Reactive Protein Blood pressure Case-Control Studies Hypertension Cardiology biology.protein Female medicine.symptom Cardiology and Cardiovascular Medicine business Biomarkers Follow-Up Studies |
| Zdroj: | The American Journal of Cardiology. 97:659-661 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2005.09.104 |
| Popis: | The presence of systemic inflammation determined by elevations in high-sensitivity C-reactive protein (hs-CRP) has been associated with persistence of atrial fibrillation (AF). The influence of inflammation markers, such as hs-CRP, on the recurrences of lone AF, however, has not been clarified. We tested the hypothesis of whether, in patients with a first paroxysmal episode of lone AF, the hs-CRP levels were elevated, and whether elevated hs-CRP could predict the recurrence rate of lone AF in patients without antiarrhythmic drugs. Using a case-control study design, the hs-CRP levels in 125 patients with a documented symptomatic first paroxysmal episode of lone AF was compared with the hs-CRP levels in 65 control patients. hs-CRP levels are presented as median values with the interquartile range (25th to 75th percentiles). The hazard ratio compared the 75th percentile of hs-CRP with the 25th percentile. In the arrhythmia group, hs-CRP was higher than in the control patients (median 0.23 mg/dl, interquartile range 0.12 to 0.49, vs 0.087 mg/dl, interquartile range 0.058 to 0.098, p |
| Databáze: | OpenAIRE |
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