Manifestations of myocardial involvement in acute reactions to penicillin∗
| Autor: | Per H. Langsjoen, Robert F. Haden |
|---|---|
| Rok vydání: | 1961 |
| Předmět: |
Bradycardia
medicine.medical_specialty Circulatory collapse Heart Diseases Penicillins Edema Internal medicine medicine Humans cardiovascular diseases Arteritis skin and connective tissue diseases business.industry Myocardium Heart medicine.disease Coronary arteries Cellular infiltration Penicillin medicine.anatomical_structure Rapid onset Cardiology sense organs medicine.symptom Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | The American Journal of Cardiology. 8:420-425 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/0002-9149(61)90162-x |
| Popis: | 1. 1. Myocardial damage as evidenced by electrocardiographic changes is reported in three cases of allergic reactions to penicillin. 2. 2. Myocardial involvement following allergic reactions has been previously demonstrated clinically, experimentally and on necropsy studies. The pathologic changes consisted of edema and cellular infiltration in the myocardium, and an arteritis of the coronary arteries. 3. 3. The importance of myocardial anoxia secondary to circulatory collapse in the production of these changes has not been well established. 4. 4. Our cases showed electrocardiographic changes in the absence of circulatory collapse. The rapid onset and transient nature of these changes is similar to allergic reactions in other, more easily observed, tissues. 5. 5. Syncope or bradycardia in allergic reactions may be evidence of myocardial involvement and justifies electrocardiographic studies. |
| Databáze: | OpenAIRE |
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