Whole brain transcriptomics of intermittently fed individuals of the marine teleost Sparus aurata
| Autor: | Panagiota Panagiotaki, O. Ntantali, Eleni Golomazou, W. Abbink, H. Miliou, Ioannis T. Karapanagiotidis, Emmanouil E. Malandrakis |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Food deprivation
Physiology Zoology RNA-Seq Biology Biochemistry Transcriptome Fish physiology Brain transcriptome Intermittent feeding Gene expression Genetics Animals Fokkerij & Genomica Molecular Biology Ion transport Gene Expression Profiling Brain Computational Biology Sea Bream Diet Fish RNA-seq Food Deprivation Animal Breeding & Genomics |
| Zdroj: | Comparative Biochemistry and Physiology-Part D: Genomics and Proteomics 36 (2020) Comparative Biochemistry and Physiology-Part D: Genomics and Proteomics, 36 |
| ISSN: | 1744-117X |
| Popis: | A major challenge in fish physiology is to understand the mechanisms underlying the transcriptomic responses of fish brain to food deprivation. Differential gene expression analysis identified in total 2240 transcripts that presented >2-fold change (adjusted p < 0.01) between each treatment and the control group (C). The identity of the transcripts was obtained with annotation against multiple public databases and they were grouped according to their expression patterns. The gene ontology terms that were substantially affected were identified by functional annotation analysis. Genes related to ion transport, cell cycle and cell adhesion were mainly regulated during fasting and refeeding. These findings contribute to identify key indicators for the molecular basis of brain functions during periods of starvation in gilthead seabream. |
| Databáze: | OpenAIRE |
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