Distinct Contributions of Dorsal and Ventral Streams to Imitation of Tool-Use and Communicative Gestures
| Autor: | Klaus Willmes, Irina Mader, Andrea Dressing, Cornelius Weiller, Charlotte S. M. Schmidt, Christoph P. Kaller, Dorothee Kümmerer, Lena Beume, Michel Rijntjes, Tobias Bormann, Markus Martin, Vera M. Ludwig, Kai Nitschke |
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| Rok vydání: | 2016 |
| Předmět: |
Dorsum
Adult Male Cognitive Neuroscience media_common.quotation_subject Insular cortex computer.software_genre Apraxia 050105 experimental psychology White matter 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Voxel medicine Humans 0501 psychology and cognitive sciences Prospective Studies media_common Aged Aged 80 and over Cerebral Cortex Transitive relation Gestures Communication 05 social sciences Middle Aged medicine.disease Imitative Behavior Magnetic Resonance Imaging Stroke medicine.anatomical_structure Female Psychology Imitation computer 030217 neurology & neurosurgery Psychomotor Performance Cognitive psychology Gesture |
| Zdroj: | Cerebral cortex (New York, N.Y. : 1991). 28(2) |
| ISSN: | 1460-2199 |
| Popis: | Imitation of tool-use gestures (transitive; e.g., hammering) and communicative emblems (intransitive; e.g., waving goodbye) is frequently impaired after left-hemispheric lesions. We aimed 1) to identify lesions related to deficient transitive or intransitive gestures, 2) to delineate regions associated with distinct error types (e.g., hand configuration, kinematics), and 3) to compare imitation to previous data on pantomimed and actual tool use. Of note, 156 patients (64.3 ± 14.6 years; 56 female) with first-ever left-hemispheric ischemic stroke were prospectively examined 4.8 ± 2.0 days after symptom onset. Lesions were delineated on magnetic resonance imaging scans for voxel-based lesion-symptom mapping. First, while inferior-parietal lesions affected both gesture types, specific associations emerged between intransitive gesture deficits and anterior temporal damage and between transitive gesture deficits and premotor and occipito-parietal lesions. Second, impaired hand configurations were related to anterior intraparietal damage, hand/wrist-orientation errors to premotor lesions, and kinematic errors to inferior-parietal/occipito-temporal lesions. Third, premotor lesions impacted more on transitive imitation compared with actual tool use, pantomimed and actual tool use were more susceptible to lesioned insular cortex and subjacent white matter. In summary, transitive and intransitive gestures differentially rely on ventro-dorsal and ventral streams due to higher demands on temporo-spatial processing (transitive) or stronger reliance on semantic information (intransitive), respectively. |
| Databáze: | OpenAIRE |
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