The acute effect of intra-aortic balloon counterpulsation during extracorporeal life support: An experimental study
| Autor: | Jasper L Selder, Loes D C Sauren, Jos G. Maessen, Koen D. Reesink, Cesare Beghi, Frederik H. van der Veen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Extracorporeal Circulation
medicine.medical_specialty Cardiac output medicine.medical_treatment Biomedical Engineering Biophysics Medicine (miscellaneous) Hemodynamics Bioengineering Pressure-volume loops Ventricular Function Left Extracorporeal law.invention Extracorporeal life support Biomaterials Afterload law Internal medicine Counterpulsation Cardiopulmonary bypass Animals Medicine Cardiac Output Ventricular function Intra-aortic balloon pump Cardiopulmonary Bypass Intra-Aortic Balloon Pumping Sheep business.industry Extracorporeal circulation Heart General Medicine Blood pressure Models Animal Cardiology Assist devices Heart-Assist Devices business |
| Popis: | Hemodynamically unstable patients supported by an extracorporeal life support (ECLS) circuit often receive additional support by intra-aortic balloon pump (IABP). However, it is not established whether support of the failing heart is improved by adjunctive IABP in both peripheral cannulation (PC) and central cannulation (CC) settings. Seven sheep were supported by an IABP and an ECLS system which were cannulated centrally as well as peripherally. In each cannulation configuration, hemodynamic and cardiac function indices were measured at baseline, ECLS, and ECLS plus IABP. The primary variables were mean coronary artery flow (Qcor), diastolic pressure time index (DPTI), left ventricular (LV) pressure-volume area (PVA), and tension time index (TTI). Additional IABP with ECLS support (CC/PC) decreased LV afterload (LV systolic peak pressure -4%, P |
| Databáze: | OpenAIRE |
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