Ipidacrine in combination therapy regimens of functional constipation
| Autor: | S K Sivkova, N P Vanchakova, Natalya P. Chernus, Roman V. Gorenkov, A S Sivkov |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
History medicine.medical_specialty Treatment response Constipation Combination therapy Endocrinology Diabetes and Metabolism adaptation mechanisms lcsh:Medicine psychological resources stress chemistry.chemical_compound Minnesota Multiphasic Personality Inventory Internal medicine Humans Medicine functional slow-transit constipation Gastrointestinal Transit ipidacrine business.industry lcsh:R Ipidacrine General Medicine Middle Aged Prognosis medicine.disease Combined Modality Therapy Regimen chemistry Mental state Aminoquinolines Functional constipation medicine.symptom Family Practice business |
| Zdroj: | Терапевтический архив, Vol 90, Iss 12, Pp 48-55 (2018) |
| ISSN: | 2309-5342 0040-3660 |
| DOI: | 10.26442/00403660.2018.12.000008 |
| Popis: | Aim. Analysis of the treatment response rates of different therapy regimens of functional constipation, including Ipidacrine, a cholinesterase inhibitor, based on assessment of adaptation and compensatory mechanisms in the therapy forecast. Materials and methods. 77 functional slow-transit constipation patients were examined after therapy regimens of functional constipation, the mean age is 44.30±14.58 y.o. Results and discussion. The treatment response rates of different therapies with Ipidacrine depends on the patient's initial adaptation and compensatory mechanisms (ACM index); certain aspects allowing to predict the expected result depending on the current mental state were identified; the severity of the state of functional constipation, ACM index and MMPI test psychometric indicators are correlated; adaptation and compensatory mechanisms of functional constipation patients were found to be reduced; the prognosis of the treatment response rates and, accordingly, the choice of the therapy regimen depend on the patient's adaptation potential (index). Conclusions. Therapy regimens for functional constipation patients should be selected on the basis of the original ACM index, behavioral pattern, degree of compliance and the patient’s age. |
| Databáze: | OpenAIRE |
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