Adaptation to Laterally Displacing Prisms in Anisometropic Amblyopia
| Autor: | Luke Gane, Herbert C. Goltz, Agnes M. F. Wong, Jaime C. Sklar |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Adolescent Daily function Sensorimotor system Adaptation (eye) Middle Aged Oculomotor function Amblyopia Adaptation Physiological eye diseases Hand position Young Adult Physical medicine and rehabilitation medicine Humans Female Prism Psychology Prism adaptation Dioptre |
| Zdroj: | Investigative ophthalmologyvisual science. 56(6) |
| ISSN: | 1552-5783 |
| Popis: | PURPOSE Using visual feedback to modify sensorimotor output in response to changes in the external environment is essential for daily function. Prism adaptation is a well-established experimental paradigm to quantify sensorimotor adaptation; that is, how the sensorimotor system adapts to an optically-altered visuospatial environment. Amblyopia is a neurodevelopmental disorder characterized by spatiotemporal deficits in vision that impacts manual and oculomotor function. This study explored the effects of anisometropic amblyopia on prism adaptation. METHODS Eight participants with anisometropic amblyopia and 11 visually-normal adults, all right-handed, were tested. Participants pointed to visual targets and were presented with feedback of hand position near the terminus of limb movement in three blocks: baseline, adaptation, and deadaptation. Adaptation was induced by viewing with binocular 11.4° (20 prism diopter [PD]) left-shifting prisms. All tasks were performed during binocular viewing. RESULTS Participants with anisometropic amblyopia required significantly more trials (i.e., increased time constant) to adapt to prismatic optical displacement than visually-normal controls. During the rapid error correction phase of adaptation, people with anisometropic amblyopia also exhibited greater variance in motor output than visually-normal controls. CONCLUSIONS Amblyopia impacts on the ability to adapt the sensorimotor system to an optically-displaced visual environment. The increased time constant and greater variance in motor output during the rapid error correction phase of adaptation may indicate deficits in processing of visual information as a result of degraded spatiotemporal vision in amblyopia. |
| Databáze: | OpenAIRE |
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