Treatment outcomes of over 1000 patients on second‐line, protease inhibitor‐based antiretroviral therapy from four public‐sector HIV treatment facilities across Johannesburg, South Africa

Autor:	Denise Evans, Kate Shearer, Lawrence Long, Ian Sanne, Rebecca Berhanu, Julia Rohr, Matthew P. Fox, Liudmyla van den Berg, Faith Moyo
Rok vydání:	2016
Předmět:	Adult Male 0301 basic medicine medicine.medical_specialty virologic suppression Anti-HIV Agents antiretroviral therapy HIV Infections Ambulatory Care Facilities Cohort Studies South Africa 03 medical and health sciences symbols.namesake 0302 clinical medicine death Internal medicine medicine Humans Attrition Protease inhibitor (pharmacology) 030212 general & internal medicine Poisson regression Hiv treatment Retrospective Studies business.industry Public sector Public Health Environmental and Occupational Health HIV Retrospective cohort study Original Articles Middle Aged Viral Load medicine.disease 030112 virology Treatment Outcome Infectious Diseases loss to follow‐up Physical therapy symbols Patient Compliance Original Article Female Parasitology second‐line business Viral load Cohort study
Zdroj:	Tropical Medicine & International Health
ISSN:	1365-3156 1360-2276
Popis:	Objectives To report predictors of outcomes of second-line ART for HIV treatment in resource-limited settings. Methods All adult ART-naive patients who initiated standard first-line treatment between April 2004-February 2012 at four public-sector health facilities in Johannesburg, South Africa, experienced virologic failure, and initiated standard second-line therapy were included. We assessed predictors of attrition (death and loss to follow-up [≥3 months late for a scheduled visit]) using Cox proportional hazards regression and predictors of virologic suppression (viral load
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070cef5032053c86e6dc87080438bff9 https://doi.org/10.1111/tmi.12804 Zobrazit plný text záznamu Plný text