Neointimal coverage of jailed side branches in coronary bifurcation lesions

Autor: Tomoko Tamada, Shiro Uemura, Ai Kawamura, Teruyoshi Kume, Ryotaro Yamada, Yoji Neishi, Koichiro Imai, Kenzo Fukuhara, Yutaka Goryo, Okamoto Hiroshi, Koyama Terumasa
Rok vydání: 2018
Předmět:
Male
Neointima
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Coronary Artery Disease
030204 cardiovascular system & hematology
Anterior Descending Coronary Artery
03 medical and health sciences
Percutaneous Coronary Intervention
0302 clinical medicine
Japan
Optical coherence tomography
Predictive Value of Tests
Internal medicine
Humans
Medicine
cardiovascular diseases
030212 general & internal medicine
Coronary bifurcation
Aged
Retrospective Studies
medicine.diagnostic_test
business.industry
Percutaneous coronary intervention
Stent
Small sample
General Medicine
Middle Aged
equipment and supplies
Coronary Vessels
Treatment Outcome
surgical procedures
operative

Cardiology
Female
Stents
Cardiology and Cardiovascular Medicine
business
Tomography
Optical Coherence

Body orifice
Zdroj: Coronary Artery Disease. 29:114-118
ISSN: 0954-6928
DOI: 10.1097/mca.0000000000000563
Popis: Objectives The jailed strut at the side-branch (SB) orifice may be a cause of delayed neointimal coverage and SB flow disturbance after single stenting to bifurcation. The aim of this study was to characterize the exact relationship between the jailed strut pattern at the SB orifice immediately after stent implantation and neointimal coverage of the jailed SB orifice in the chronic phase. Patients and methods A total of 29 bifurcation (left anterior descending coronary artery and diagonal branch) lesions treated by optical coherence tomography-guide single-stent implantation and followed at 18 months after a percutaneous coronary intervention were included in this study. Results Using three-dimensional optical coherence tomography images, the jailed stent strut pattern was classified into two groups on the basis of the presence of a stent strut link at the SB orifice (link group: n=11, and no-link group: n=18). SB orifice obstruction by neointima was significantly greater in the link group than in the no-link group during the 18-month follow-up period (26.8±21.9 vs. 9.5±22.1%, P=0.049). Conclusion This single-center observational study with a small sample size showed that a jailed strut pattern at the SB orifice might be related to neointimal coverage of the SB orifice in bifurcation lesions treated with single-stent implantation. Further large-scale studies with long-term follow-up will be necessary to determine the exact relationship between the jailed strut pattern at the SB orifice and SB flow disturbance because of delayed neointimal coverage as well as clinical outcome.
Databáze: OpenAIRE