Mitotic activity in colorectal mucosa of healthy subjects in two Italian areas with different dietary habits

Autor: Antonio Russo, Andrea Montigiani, Piero Dolara, Alfonso Lagi, Domenico Palli, Ugo Ginanneschi, Marina Rizzi, Rosa Valanzano, Franca Bianchini, Maria Teresa Spagnesi, Francesco Tonelli, Francesco Cipriani, Giovanna Caderni, Massimo Gabbrielli
Rok vydání: 1993
Předmět:
Zdroj: Nutrition and Cancer. 19:263-268
ISSN: 1532-7914
0163-5581
DOI: 10.1080/01635589309514257
Popis: The proliferative activity was evaluated in colorectal biopsies of 39 healthy subjects living in two distinct geographical areas, Trieste in northern and Florence in central Italy. Subjects living in Trieste had a significantly higher mitotic activity compared with subjects living in Florence (mitoses/cells counted × 100 were 0.17 ± 0.04 in Trieste and 0.089 ± 0.02 in Florence). The results of a dietary questionnaire also showed that subjects in Trieste consumed significantly fewer starches, fibers, nitrites, and proteins. However, no correlation was evident between the consumption of these nutrients and intestinal proliferation.
Databáze: OpenAIRE