A preliminary report of fine-needle aspiration biopsy in superficially accessible lesions in children

Autor: L M Ntele, B A Salami, O Akiode, A A Musa, A M O Shonubi
Rok vydání: 2004
Předmět:
Zdroj: West African Journal of Medicine; Vol 23, No 3 (2004); 221-223
ISSN: 0189-160X
Popis: Background: Fine-Needle Aspiration Biopsy (FNAB) is a diagnostic technique which has achieved widespread use and acceptance. Its clinical use has continued to widen with the availability of more sophisticated methods of imaging. Its minimal invasiveness, cheap cost and easy application make it a technique of choice in investigating swellings even in children. Aims and objectives: To investigate the reliability, safety and diagnostic value of FNAB in superficial masses including lymph nodes in children. Patients and methods: Superficial masses and lymph nodes of twenty consecutive children aged 2-13years were subjected to FNAB. Open biopsies were also performed on them to validate the FNAB. All specimens were subjected to examination by a cytopathologist and a histopathologist. Results: Nine of the patients (45%) had malignant diseases (lymphoma and osteosarcoma); seven had tuberculous lymphadenopathy while four had reactive lymphadenitis. Open biopsies corroborated these findings. There were no false-negative or false-positive cytology results from aspirates. There were no complications related to the procedures. Conclusion: Fine-needle aspiration biopsy is a reliable, safe, less invasive and relatively cheaper alternative method of establishing a pathologic diagnosis, compared to open biopsy, in children. Key Words: Cytology, Children, Fine needle aspiration biopsy. Resume Introduction:- La Biopsie d'aspiration d l'aiguille fine ‘Fine-Needle aspiration Biopsy' (FNAB) est une technique diagnostique l'utisation et acceptabilite de laquelle est largement repandue. Son utilization clinique continue a s'elargir avec la disponibilite de la methode d'imagerie medicale plus sophistiquee. Sa nature invasive minimale, du bon marche et application facile donnent a cette technique de choix dans Ie diagnostic de la tumefaction meme chez des enfants. Buts et Objectifs:- Etudier la fiabilite, Ie sans danger et la valeur diagnostique de FNAB dans des masses superficielle y compris ganglion lymphatique chez des enfants. Patients et Methodes:- Des masses superficielles et des ganglions lymphatiques de vignt enfants consecutifs âges 2 - 13 ans ant subi la FNAB. On avait egalement opere les biopsies couvertes chez des patients afin de confirmer la FNAB. Tous les specimens ont ete exposes a I'examen par un cytopathologiste et un histopathologiste. Resultats:- Neuf d'entre les patients soit 45% etaient atteints des maladies malignes (lymphoma et osteosarcome); sept atteints de la lymphadenopathie reactive tandis que quatre atteints de la tuberculose lymphadenite. Des biopsies ouvertes ont confirme ces resultats. II n'y avait pas de resultats cytologique fausse positive ou fausse negative a partir des aspirers. II n' y avait aucune complication liee aux protocols. Conclusion:- La biopsie de l'aspiration d'aiguille fine est fiable, sans danger, moins invasive et relativement du tres bon marche un autre methode de confirmer un diagnostic pathologique par rapport a la biopsie ouverte chez des enfants. West African Journal of Medicine Vol.23(3) 2004: 221-223
Databáze: OpenAIRE