Evaluation of serum leptin concentration in Behçet's disease with ocular involvement
| Autor: | Melih Kurt, Sevim Kavuncu, Serap Ortaç, Feray Koç, Pinar Cakar Ozdal, Esin Firat, Buğra Eryüksel |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Leptin Male medicine.medical_specialty genetic structures Neutrophils Disease Behcet's disease Blood Sedimentation Gastroenterology Body Mass Index Cellular and Molecular Neuroscience Leukocyte Count Internal medicine medicine Humans In patient business.industry Behcet Syndrome digestive oral and skin physiology Middle Aged medicine.disease eye diseases Sensory Systems stomatognathic diseases Ophthalmology Endocrinology Serum leptin business Body mass index hormones hormone substitutes and hormone antagonists |
| Zdroj: | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 243(11) |
| ISSN: | 0721-832X |
| Popis: | To assess the correlation between the serum leptin concentration and ocular involvement in patients with Behçet's disease.The study included 28 male consecutive patients with Behçet's disease ( group A, aged 19-59, median 35.5 years) and 15 male healthy control subjects ( group B, aged 25-45, median 35 years). The body mass index (BMI) was calculated for each subject at the study enrollment stage. We measured serum leptin, neutrophil count and erythrocyte sedimentation rate (ESR). Kruskal-Wallis variance analysis and the Mann-Whitney U-test were used for statistical analysis.The age and BMI between the patients with ocular Behçet's disease and the control group were not different. White cell count and ESR values were found to be significantly higher among patients with Behçet's disease and ocular involvement (p0.001). The median serum leptin concentrations were as follows: group A: 2.66 (0.57-7.02 ng/ml) and in group B: 2.55 (1.55-7.82 ng/ml). There was no statistically significant difference between the groups.Serum leptin level does not correlate with ocular involvement in patients with Behçet's disease. |
| Databáze: | OpenAIRE |
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