In-Hospital Outcomes and Prevalence of Comorbidities in Patients with St-Elevation Myocardial Infarction with and without Infective Endocarditis: Insight from the National Inpatient Sample (2013-2014)
| Autor: | Asim Kichloo, Nicholas Haddad, Bashar Al Jayyousi, Farah Wani, Khalil Kanjwal, Melissa Beshay, Michael Aljadah, Ronak Soni, Beth Bailey, Jagmeet P. Singh, Shakeel Jamal, Michael Albosta |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Comorbidity 030204 cardiovascular system & hematology General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Aortic valve replacement Internal medicine Prevalence medicine Humans Endocarditis Hospital Mortality cardiovascular diseases 030212 general & internal medicine Myocardial infarction Healthcare Cost and Utilization Project Stroke Inpatients business.industry Mitral valve replacement General Medicine Acute Kidney Injury Length of Stay medicine.disease surgical procedures operative Infective endocarditis Concomitant ST Elevation Myocardial Infarction Respiratory Insufficiency business |
| Zdroj: | Journal of Investigative Medicine. 69:756-760 |
| ISSN: | 1708-8267 1081-5589 |
| Popis: | In patients with infective endocarditis (IE), ST-elevation myocardial infarction (STEMI) is an uncommon phenomenon. Due to limited data, we intend to evaluate the clinical outcomes in hospitalized patients with STEMI with and without underlying IE. Mortality and morbidity are exponentially worse in STEMI with concomitant IE when compared with without IE. Patients with primary diagnosis of STEMI with and without IE were identified by querying the Healthcare Cost and Utilization Project database of the National Inpatient Sample for the years 2013 and 2014 based on International Classification of Diseases, Ninth Revision codes. During 2013 and 2014, a total of 117,386 patients were admitted with the principle diagnosis of STEMI, out of whom 305 had comorbid IE. There was a significantly increased in-hospital mortality (27.5% vs 10.8%), length of stay (LOS) (14 days vs 5 days), acute kidney injury (AKI; 44.9% vs 18.7%), stroke (23.6% vs 3%), aortic valve replacement (9.5% vs 0.3%), mitral valve replacement (0.2%-5.2%), sepsis (50% vs 6%) and acute respiratory failure (36.7% vs 16.7%) in patients with STEMI with IE when compared with patients with STEMI and without comorbid IE. STEMI without IE had a higher number of angiographies (58.7% vs 25.9%) and percutaneous coronary interventions (50.7% vs 14.4%) during the hospital course when compared with STEMI with IE. In conclusions, hospitalized patients with STEMI with a concurrent diagnosis of IE are at higher risk of in-hospital mortality, increased LOS, AKI, stroke, valve replacements, and acute respiratory failure. |
| Databáze: | OpenAIRE |
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