Measurement of central corneal thickness by high-resolution Scheimpflug imaging, Fourier-domain optical coherence tomography and ultrasound pachymetry
Autor: | Jinhai Huang, Qinmei Wang, Daizong Wen, Wuhe Chen, Shihao Chen, David Huang |
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Rok vydání: | 2010 |
Předmět: |
Adult
Male Materials science Adolescent Corneal Pachymetry genetic structures Scheimpflug principle High resolution Cornea Young Adult Optics Optical coherence tomography Reference Values Photography medicine Humans Prospective Studies Fourier domain Observer Variation Reproducibility Fourier Analysis medicine.diagnostic_test business.industry Reproducibility of Results Ultrasound pachymetry Organ Size General Medicine Repeatability eye diseases Ophthalmology Female sense organs Tomography business Tomography Optical Coherence Biomedical engineering |
Zdroj: | Acta Ophthalmologica. 90:449-455 |
ISSN: | 1755-375X |
Popis: | Purpose: To compare the repeatability and reproducibility of central corneal thickness (CCT) measurements by high-resolution (HR) rotating Scheimpflug imaging and Fourier-domain optical coherence tomography (FD-OCT). CCT measurements were compared to those determined by ultrasound pachymetry (UP). Methods: In 35 healthy eyes, intra-observer repeatability for HR Scheimpflug (Pentacam) and FD-OCT (RTVue) systems was determined in consecutive images taken by an observer in the shortest time possible. Imaging was repeated again by a second observer to evaluate inter-observer reproducibility. The CCT measurements were compared among Scheimpflug, FD-OCT and UP images. Results: Mean coefficients of repeatability were 0.48% for Scheimpflug and 0.26% for FD-OCT. For Scheimpflug, the coefficient of inter-operator reproducibility was 0.87%. For FD-OCT, the coefficient of inter-operator reproducibility was 0.45%. The CCT measurements by Scheimpflug, OCT and UP images were (mean ± standard deviation) 521.7 ± 27.6 μm, 510.8 ± 28.6 μm and 516.5 ± 27.6 μm, respectively. The differences between instruments were statistically significant. The 95% limits of agreement in CCT were −0.7 to 22.5 μm for Pentacam-OCT, −13.4 to 24.0 μm for Pentacam-UP and −26.7 to 15.4 μm for OCT-UP. There was a high degree of correlation between CCT measured by all 3 methods. Conclusion: Noncontact measurements of CCT with HR Scheimpflug and FD-OCT systems yielded excellent repeatability and reproducibility and can be used interchangeably. Although both devices were comparable with UP; in clinical practice, the measurements acquired by optical modalities are not directly interchangeable with UP measurements. |
Databáze: | OpenAIRE |
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