Smokeless tobacco use and risk of oral cavity cancer
| Autor: | Abubaker Shahid, Shahzeb Khan, Misbah Masood, Hasan Nisar, Ismat Fatima, Ahmed Farooq, Irfan Ullah Khan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Tobacco Smokeless 030204 cardiovascular system & hematology Oral cavity Article Tobacco Use Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Odds Ratio Humans Medicine Pakistan Snuff Aged risk Mouth 0303 health sciences 030306 microbiology business.industry Incidence (epidemiology) Betel leaf snuff Cancer General Medicine Odds ratio Middle Aged medicine.disease Confidence interval stomatognathic diseases Smokeless tobacco Case-Control Studies Mouth Neoplasms oral cavity Smokeless tobacco risk snuff oral cavity business |
| Zdroj: | Turkish Journal of Medical Sciences Volume: 50, Issue: 2 291-297 |
| ISSN: | 1303-6165 1300-0144 |
| DOI: | 10.3906/sag-1809-11 |
| Popis: | Background/aim: Smokeless tobacco has been associated with oral cavity cancer for several decades. The incidence of oral cavity cancer is higher in some parts of the world especially South and South-East Asia including Pakistan. The aim of current study was to evaluate the risk of oral cavity cancer among smokeless tobacco users in our country. Materials and methods: A case-control study was conducted between November 2016 and September 2017. Patients diagnosed with oral cavity cancer receiving treatment were included as cases and the attendants of various cancer patients visiting the hospital during the study period were included in the study as controls. Odds ratios OR and 95% confidence intervals CI were calculated and all reported P-values were considered significant at < 0.05. Results: The crude OR for the "ever smokeless tobacco users" among cases and controls came out to be 4.98 95%CI; 2.76-9.01 . The OR for snuff users among cases and controls was 4.82 95%CI; 2.37-9.80 and that for betel leaf users was 4.42 95%CI; 1.66-11.91 after adjusting for smoking and age. Conclusion: Our study provided strong evidence for snuff and betel leaf to be independent risk factors for oral cavity cancer. |
| Databáze: | OpenAIRE |
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