A review of phototherapy protocols for psoriasis treatment
| Autor: | Christian R. Halvorson, Steven R. Feldman, Jerry Bagel, Whitney J. Lapolla, Brad A. Yentzer |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Dermatology chemistry.chemical_compound Keratolytic Agents Clinical Protocols Psoriasis Area and Severity Index Psoriasis medicine Ultraviolet light Humans Outpatient clinic Carotid Stenosis Dosing skin and connective tissue diseases PUVA Therapy Psoralen integumentary system business.industry medicine.disease Acitretin Clinical trial Methotrexate Treatment Outcome chemistry PUVA therapy Lasers Excimer Ultraviolet Therapy business Immunosuppressive Agents |
| Zdroj: | Journal of the American Academy of Dermatology. 64:936-949 |
| ISSN: | 0190-9622 |
| DOI: | 10.1016/j.jaad.2009.12.054 |
| Popis: | Phototherapy is a mainstay in the treatment of psoriasis and is available as psoralen plus UVA (PUVA), broadband UVB (BB-UVB), and narrowband UVB (NB-UVB). Phototherapy can be administered in the hospital, outpatient clinic, or in the patient's home. The purpose of this review is to provide some practical guidance to general dermatologists and residents on the specifics of using phototherapy, which, despite its decreasing use, remains one of our most safe and effective treatment strategies for psoriasis care. We conducted a literature review of home phototherapy, BB-UVB, NB-UVB, and PUVA phototherapy using PubMed, MD Consult, and reference lists. A variety of protocols for BB-UVB, NB-UVB, and PUVA have been used in clinical trials. NB-UVB is more effective than BB-UVB and safer than PUVA. Typical regimens for NB-UVB involve dosing 3 times per week for at least 3 months. Treatment must be independently developed to suit each participant's needs. Ultraviolet light is an effective, relatively safe modality that is a valuable tool in the treatment of psoriasis. NB-UVB phototherapy is considered the first-line treatment for extensive plaque type psoriasis. |
| Databáze: | OpenAIRE |
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