| Popis: |
Sweat retention, i. e. faulty and reduced outpouring of elaborated sweat, may be the result of various and differing mechanisms. Some of these have been discussed in detail in previous communications. These include the studies of horny plugging as found in prickly heat and tropical anidrotic asthenia (1, 2, 3); the similar plugging seen on occasion in ichthyosiform itching eruptions and in dry forms of atopic dermatitis, etc. (4). Another mechanism leading to sweat retention is that described as a sequela in certain cases of lichenoid atabrine dermatitis. In the atabrine cases studied by our group, the process which leads to sweat retention appears to be a scarlike obliteration of the superficial portion of sweat ducts, rather than the mere plugging of their orifices. These and other mechanisms leading to retention of secreted sweat all have in common the fact that they follow certain clinical changes or insults to the skin (heat, humidity, dry eruptions, scarring atopic dermatitis, ichthyosiform dryness, other faults in keratinization, etc.). Another group of causes of reduced or inhibited outpouring of sweat can be classed together on the common basis that they are all the result of conditions produced experimentally or deliberately. To this class may be reckoned the reduced sweating after application of antiperspirants (5). Other experimental mechanisms whereby sweat-outpouring can be reduced and sweat retention can occur have recently been brought to light by the fundamental studies of O'Brien (6) with local application of fat-solvents, and by the important experiments of Shelley, Horvath, Weidman and Pillsbury (7). These latter authors observed that electrophoretic production of anidrosis was regularly successful only at the site of the anode, more or less regardless of what solutions |
