Development of a Conceptual Model of Chronic Hand Eczema (CHE) Based on Qualitative Interviews with Patients and Expert Dermatologists
| Autor: | Kate Burrows, Ole E. Sørensen, Elke Weisshaar, Julie Hahn-Pedersen, Laura Grant, Rob Arbuckle, Thomas L. Diepgen, Lotte Seiding Larsen, Donald V. Belsito |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male 030213 general clinical medicine Health-related quality of life media_common.quotation_subject Symptom Eczema Embarrassment Review Disease Chronic hand eczema Young Adult 03 medical and health sciences 0302 clinical medicine Quality of life Qualitative research Patient experience Humans Medicine Pharmacology (medical) Prospective Studies Interview Aged media_common Literature review Sleep disorder Hand eczema integumentary system business.industry General Medicine Middle Aged Models Theoretical Hand medicine.disease United States Impact 030220 oncology & carcinogenesis Chronic Disease Conceptual model Female Symptom Assessment business Clinical psychology |
| Zdroj: | Advances in Therapy |
| ISSN: | 1865-8652 0741-238X |
| Popis: | Introduction Chronic hand eczema (CHE) is a relapsing inflammatory dermatologic disease. Signs and symptoms can have a significant impact on patients’ health-related quality of life (HRQoL). The aim of this study is to characterize the core signs, symptoms and impacts of CHE to develop a conceptual model. Methods A structured literature search and qualitative interviews with 20 adult CHE patients in the US and 5 expert dermatologists were conducted to explore the patient experience of CHE signs, symptoms and impacts. Findings were used to support the development of a conceptual model. Results There was a paucity of CHE qualitative research in the literature, supporting the need for the prospective qualitative research. The primary signs and symptoms identified from the literature review and interviews included itch, dryness, cracking, pain, thickened skin and bleeding. The most salient impacts included embarrassment and appearance concerns, frustration, impacts on work and sleep disturbance. Saturation was achieved for all signs, symptoms and impact concepts. Conclusions Findings from this literature review and in-depth qualitative interviews supported the development of a comprehensive conceptual model documenting the signs, symptoms and impacts relevant to CHE patients. Such a model is of considerable value given the lack of existing studies in the literature focused on the qualitative exploration of the CHE patient experience. Limitations included the patient sample being only from the US and not including some CHE subtypes. |
| Databáze: | OpenAIRE |
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