Pretherapeutic staging of locally advanced cervical cancer: Inframesenteric paraaortic lymphadenectomy accuracy to detect paraaortic metastases in comparison with infrarenal paraaortic lymphadenectomy
| Autor: | Emmanuelle Tresch-Bruneel, Yves Borghesi, Henri Azaïs, Fabrice Narducci, Clothilde Petitnicolas, Eric Leblanc, A. Cordoba, Lucie Bresson, Louise Ghesquière |
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| Přispěvatelé: | Centre Régional de Lutte contre le Cancer Oscar Lambret [Lille] (UNICANCER/Lille), Université Lille Nord de France (COMUE)-UNICANCER, Université de Lille-UNICANCER, SALZET, Michel |
| Rok vydání: | 2017 |
| Předmět: |
Oncology
Adult medicine.medical_specialty [SDV]Life Sciences [q-bio] Locally advanced Uterine Cervical Neoplasms Inferior mesenteric artery Paraaortic lymphadenectomy 03 medical and health sciences 0302 clinical medicine Paraaortic lymph nodes Histological subtype Nodal status Internal medicine medicine.artery Positron Emission Tomography Computed Tomography medicine Humans Laparoscopy Aged Neoplasm Staging Cervical cancer 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics and Gynecology Middle Aged medicine.disease 3. Good health [SDV] Life Sciences [q-bio] Dissection 030220 oncology & carcinogenesis Lymphatic Metastasis Lymph Node Excision Surgery Female Radiology Lymph Nodes Para-aortic lymphadenectomy business |
| Zdroj: | Gynecologic Oncology Gynecologic Oncology, Elsevier, 2017, 147 (2), pp.340-344. ⟨10.1016/j.ygyno.2017.09.012⟩ Gynecologic Oncology, 2017, 147 (2), pp.340-344. ⟨10.1016/j.ygyno.2017.09.012⟩ |
| ISSN: | 1095-6859 0090-8258 |
| DOI: | 10.1016/j.ygyno.2017.09.012⟩ |
| Popis: | International audience; Background: Extended-field chemoradiation therapy is usually performed in patients with locally advanced cervical cancer (LACC) and paraaortic (PA) node metastases. Considering the very low rate of skip metastases above inferior mesenteric artery, ilio-inframesenteric paraaortic lymph node dissection (IM-PALND) seems to be an adequate pattern of PALND. Our objective was to assess the accuracy of this management to determine PA nodal status in comparison with infrarenal paraaortic lymphadenectomy (IR-PALND) in case of squamous or glandular cervical cancer.Methods: All patients with LACC and negative MRI and PET/CT imaging at paraaortic level had laparoscopic staging (followed, if negative, by extraperitoneal paraaortic lymphadenectomy). From January 2011 to September 2015, patients who had IM-PALND were included and were compared to a previous historical series of IR-PALND patients. The two groups differed only at the upper level of dissection. Characteristics of nodal involvement at paraaortic level depending on level of dissection, PET/CT imaging and histology were studied.Results: 119 women were included in our study, with 56 patients in the IM-PALND group and 63 in the IR-PALND group. In the IM-PALND group, fewer nodes were resected (p |
| Databáze: | OpenAIRE |
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