Supplementary Figures from JAM-C Identifies Src Family Kinase-Activated Leukemia-Initiating Cells and Predicts Poor Prognosis in Acute Myeloid Leukemia

Autor: Michel Aurrand-Lions, Norbert Vey, Stéphane J.C. Mancini, Yves Collette, Jean-Marie Boher, Ghislain Bidaut, Remy Castellano, Marie-Joelle Mozziconacci, Anne-Sophie Chretien, Camille Montersino, Laurent Pouyet, Samuel Granjeaud, Arnauld Sergé, Abdessamad El-Kaoutari, Christophe Zemmour, Cyril Fauriat, Florence Bardin, Maria De Grandis
Rok vydání: 2023
DOI: 10.1158/0008-5472.22416126
Popis: Supplementary Figures S1 to S7. S1 shows JAM-C, CD90 and CD45RA expression in leukemic fraction. S2 shows JAM-C expression in leukemic cells and HSPCs. S3 shows JAM-C expression in cell lines and genes differentially expressed between KG1/JAM-CNeg and KG1/JAM-CPos variant cell lines. S4 shows characterization of engrafting and non-engrafting AML patient samples. S5 shows cell cycle and proliferation properties of KG1/JAM-CNeg and KG1/JAM-CPos variant cells. S6 shows signaling pathways in KG1/JAM-CNeg and KG1/JAM-CPos. S7 shows comparison of SFK phosphorylation in CD45dimCD34+ and CD45dimCD34- leukemic cells.
Databáze: OpenAIRE