Isolation of fibrinogen from plasma by affinity chromatography on insolubilized fibrinogen (FG-ag) and insolubilized fibrin-monomer (FM-ag)

Autor:	F.R. Matthias, H.G. Lasch, G. Hocke
Rok vydání:	1975
Předmět:	Chromatography Fibrinogen Hematology Electrophoresis Disc Fibrin Monomer Chromatography Affinity Fibrin Fibrinogen Degradation Products chemistry.chemical_compound Thrombin Solubility chemistry Affinity chromatography medicine Urea Fibrinmonomer After treatment medicine.drug
Zdroj:	Thrombosis Research. 7:861-870
ISSN:	0049-3848
DOI:	10.1016/0049-3848(75)90089-4
Popis:	Insolubilized fibrinmonomer, which is converted from insolubilized fibrinogen by thrombin action, adsorbs soluble fibrinogen from solutions or plasma. After treatment with 6 molar urea without removal of the fibrinopeptides insolubilized fibrinogen gets a high affinity for soluble fibrinogen, too. Insolubilized fibrinmonomer and urea-treated insolubilized fibrinogen are suitable adsorbents for the purification of fibrinogen from plasma by affinity chromatography.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c2ce638a673d61a47f7725a608fe5b https://doi.org/10.1016/0049-3848(75)90089-4 Zobrazit plný text záznamu