Data Supplement from Calpain-Mediated Integrin Deregulation as a Novel Mode of Action for the Anticancer Gallium Compound KP46

Autor: Walter Berger, Bernhard K. Keppler, Petra Heffeter, Rosa Lemmens-Gruber, Christian R. Kowol, Sushilla Schoonhoven, Nastasia Wilfinger, Karin Nowikovsky, Thomas Schöfl, Martin Holcmann, Gernot Walko, Theresa Tuder, Johannes Gojo, Ute Jungwirth
Rok vydání: 2023
DOI: 10.1158/1535-7163.22501641.v1
Popis: Supplementary Figure 1. Role of p53 status and mitochondrial membrane depolarization in KP46-induced cell death Supplementary Figure 2. Expression and localization changes of pro- and anti-apoptotic Bcl-2 family members in response to KP46 treatment Supplementary Figure 3. Impact or KP46 on integrin β1 expression and subcellular localization in cancer cells Supplementary Figure 4. Alteration in intracellular Ca2+ levels in HCT-116 cells upon KP46 treatment Supplementary Figure 5 Effect of extracellular calpain inhibition on KP46 sensitivity in A427 and HCT-116 cells
Databáze: OpenAIRE