Flow rate and chemistry of parotid saliva related to dental caries and gingivitis in patients with thalassaemia major

Autor: Anestis Mavridis, Spyros Vasakos, Haritini Fatourou, Peter Lapatsanis, Antigone Siamopoulou-Mavridou, Emanuel Galanakis
Rok vydání: 2009
Předmět:
Male
Immunoglobulin A
medicine.medical_specialty
Saliva
Adolescent
Saliva/*chemistry/immunology/secretion
Dentistry
Dental Caries
Gastroenterology
chemistry.chemical_compound
Gingivitis
stomatognathic system
Internal medicine
Immunoglobulin A
Secretory/analysis
Parotid Gland
Humans
Medicine
In patient
Child
General Dentistry
Thalassaemia major
biology
DMF Index
business.industry
Gingivitis/*etiology/immunology
beta-Thalassemia
Immunoglobulin Isotypes/analysis
Parotid Gland/secretion
beta-Thalassemia/*complications/immunology/physiopathology
Parotid gland
Immunoglobulin Isotypes
stomatognathic diseases
medicine.anatomical_structure
chemistry
Immunoglobulin A
Secretory
biology.protein
Female
Parotid saliva
Periodontal Index
Lysozyme
medicine.symptom
Secretory Rate
business
Dental Caries/*etiology/immunology
Zdroj: International Journal of Paediatric Dentistry. 2:93-97
ISSN: 0960-7439
DOI: 10.1111/j.1365-263x.1992.tb00016.x
Popis: Twenty-one child patients with thalassaemic major (TM) and 83 healthy control children were examined for dental caries and gingivitis. Stimulated parotid gland secretions were collected from each child. Parotid saliva flow rate was measured and the saliva samples were tested for calcium, phosphorus, potassium, sodium, urea, lysozyme and immunoglobulin levels (IgA, IgG, IgM). The results showed that dental caries experience was significantly higher in the TM group. Parotid saliva flow rates in TM patients were not significantly different from those in the healthy controls. However, the median saliva concentrations of phosphorus and IgA were significantly lower in the patients than in the controls. The concentration of lysozyme was also lower in the TM group, but the difference was not statistically significant. The findings could provide an explanation for the higher dental caries experience and gingivitis observed in the TM group. Int J Paediatr Dent
Databáze: OpenAIRE
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