Production of influenza antibodies by lymphocytes of the respiratory tract
| Autor: | L. V. Solilova-Bozhenko, E. N. Agranovskaya, A. I. Mal'tseva, Ya. S. Shvartsman |
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| Rok vydání: | 1975 |
| Předmět: |
Influenza vaccine
Orthomyxoviridae Immunization Secondary Biology Antibodies Viral General Biochemistry Genetics and Molecular Biology Virus Microbiology Immunity medicine Animals Humans Lymphocytes Child Antigens Viral General Medicine biology.organism_classification Rats Trachea medicine.anatomical_structure Immunization Immunology Adenoids Antibody Formation biology.protein Nasal administration Antibody Respiratory tract |
| Zdroj: | Bulletin of experimental biology and medicine. 77(7) |
| ISSN: | 0007-4888 |
| Popis: | Antibody production against influenza virus by lymphocytes of the human nasopharyneal tonsils and the tracheal wall of rats was investigated. Atibody-producing cells were found in preparations of lymphadenoid tissue removed in the postepidemic period. Intranasal immunization of rats with living influenza vaccine led to the accumulation of producer cells in the tracheal wall and of antibodies in the secretions of the respiratory tract. Reimmunization was followed by a well-marked secondary response. A characteristic feature of secretory immunity is the slower formation of producer cells and of antibodies than is observed in the system of general immunity. |
| Databáze: | OpenAIRE |
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