The prevalence of hypercapnia during acute infection in children on chronic noninvasive ventilation: A retrospective study
| Autor: | Evelyn Wyckmans, Kim Van Hoorenbeeck, Ine van Eekelen, Sophie R. de Leede, Tessi Beyltjens, Sophie Installe, Fleur F. W. van Ginneken, Stijn Verhulst |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Adolescent Respiratory rate medicine.medical_treatment Infections Hypercapnia 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Positive airway pressure Prevalence Humans Medicine Continuous positive airway pressure Child Prospective cohort study Retrospective Studies Pediatric intensive care unit Noninvasive Ventilation Continuous Positive Airway Pressure business.industry Infant Newborn Infant Retrospective cohort study 030228 respiratory system Child Preschool Pediatrics Perinatology and Child Health Emergency medicine Breathing Female Human medicine medicine.symptom business |
| Zdroj: | Pediatric pulmonology |
| ISSN: | 1099-0496 8755-6863 |
| DOI: | 10.1002/ppul.24811 |
| Popis: | Background/Aim Children on chronic noninvasive ventilation are at risk for nonelective hospitalizations, mainly for acute infections. This study examined the prevalence of hypercapnia in children on chronic ventilatory support during an acute admission. Methods This retrospective study included children aged 0 to 18 years who regularly used bilevel positive airway pressure or continuous positive airway pressure at home, and who were diagnosed with an acute infection, and were hospitalized at the pediatrics department or pediatric intensive care unit. Capillary blood gas analysis and parameters of the built-in software of the home ventilator were recorded. Results Among the 43 cases included, hypercapnia was prevalent in 23% with a mean partial pressure of carbon dioxide of 51.7 +/- 6.4 mm Hg. These children also had lower oxygen saturation levels. The respiratory rate 48 hours before admission was significantly higher in the hypercapnic group and the volume guarantee mode was less frequently used in the hypercapnic group. Conclusion Approximately, a quarter of the cases of chronic home ventilation experience hypercapnia during an acute infection. Our data warrant a prospective study on the monitoring of respiratory rate in patients with chronic respiratory insufficiency as an indicator for hospitalizations with hypercapnia; we also recommend the use of volume guarantee mode of ventilation to prevent hypercapnia. |
| Databáze: | OpenAIRE |
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