Acute metformin administration increases mean power and the early Power phase during a Wingate test in healthy male subjects
| Autor: | Pedro Balikian, Victor José Bastos-Silva, Alisson H Marinho, Sara Learsi, José Bruno Bezerra da Silva, Filipe Antônio de Barros Sousa, Gustavo Gomes de Araujo |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Physical Exertion Energy metabolism 030209 endocrinology & metabolism Physical Therapy Sports Therapy and Rehabilitation Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Orthopedics and Sports Medicine Lactic Acid Muscle Strength Wingate test Cross-Over Studies business.industry Reproducibility of Results 030229 sport sciences General Medicine Healthy Volunteers Metformin Endocrinology AMPK activity Exercise Test business Anaerobic exercise medicine.drug |
| Zdroj: | European Journal of Sport Science. 22:1065-1072 |
| ISSN: | 1536-7290 1746-1391 |
| Popis: | The present study tested the hypothesis that acute metformin would increase peak power measured during a Wingate test. Fourteen men (24 ± 6 years; 75.8 ± 10.2 kg; 177 ± 7 cm) participated in four test sessions, conducted in a crossover, counterbalanced, double-blind model. The first and second sessions consisted of anthropometric measurements and one Wingate test per day to assess test-retest reliability. In the last two sessions, the Wingate tests were performed on metformin (500 mg capsule, 1 hour before) or placebo (cellulose capsule, 1 hour before) condition. No differences were found between the placebo and metformin for peak power (1056.8 ± 215.8 W vs. 1095.2 ± 199.3 W, respectively |
| Databáze: | OpenAIRE |
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